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Astragalus Root Herbs Extract Powder "Immune System" Astrag Polysaccharide >80% buy in Bangbu
Buy Astragalus Root Herbs Extract Powder "Immune System" Astrag Polysaccharide >80%
Astragalus Root Herbs Extract Powder "Immune System" Astrag Polysaccharide >80%

Astragalus Root Herbs Extract Powder "Immune System" Astrag Polysaccharide >80%

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Description

Name】: Astragalus Root Extract

【CAS :9005-38-3

Plants Latin name: Astragalus membranaceus (Fisch.) Bge.

Plant Source]: for the legume mongholicus root extract.

The nature of the product: Brown-yellow or off-white powder.

Active ingredients: astragaloside, astragalus polysaccharide

Pharmacological effects: enhance immunity, enhance energy, anti-fatigue, anti-mutagenic, hepatoprotective, inhibit osteoclast role. The Astragalus polysaccharide with lowering blood pressure, lower cholesterol and triglycerides, elevated the role of high-density lipoprotein; prevention and treatment of cardiovascular and cerebrovascular diseases, such as atherosclerosis, coronary artery disease, peripheral vascular disease, and hyperlipidemia and so on. Astragaloside has a significant role in lowering blood glucose, glycosylated hemoglobin and urine protein may reduce the renal cortex and serum AGEs Astragaloside has antioxidant properties, and aldose reductase inhibition also inhibit mesangial cell proliferation, reduce the role of renal hypertrophy. Astragaloside appropriate excipients, can be made into oral preparations, it is used for prevention and treatment of diabetic nephropathy

 

 

This product has enhance immunity, enhance energy, anti-fatigue, anti-mutagenic, hepatoprotective, inhibit osteoclast. Traditional Chinese medicine Astragalus qi Sun, solid form antiperspirant, the care products abscess, diuresis swelling, sore myogenic effect. Modern pharmacological studies have shown that, the astragalus with enhanced immune function, cardiac step-down, hypoglycemic, diuretic, anti-aging, anti-fatigue, Helps Strengthen Immune Response, anti-viral, sedative, analgesic effects.

One pairs of the role of the immune system

The impact of the non-specific immune function

Astragalus polysaccharide (APS) enables mice markedly enhanced phagocytosis of sheep red blood cells percentage and index. Astragalus polysaccharide monomers polysaccharide further separation: 123, respectively experiment results polysaccharide can increase spleen weight and number of cells, but inhibition of spleen cells to sheep red blood cells of the immune responses. 2 is a similar, but weaker, polysaccharides 3 does not work. Astragalus the saponins can promote lymph node B cell proliferation, differentiation and plasma cell antibody formation. The astragalus promote mouse lymphocytes sheep blood cells of the immune-specific rosette formation. The astragalus polysaccharides obvious enhance macrophage phagocytosis of luminous intensity and inhibit the release of PGE2, but further promote the release of TNF. Cyclooxygenase inhibition ibuprofen significantly inhibited the release of PGE2 and TNF, had no significant effect on phagocytosis. Can prompt the immune activator and cyclooxygenase inhibitor combination, the new program is expected to be wound infection medication.

Humoral immune function

Astragalus significant role in promoting normal body's antibody generation capabilities. Astragalus humoral immunity, enhance mononuclear phagocytic activity of macrophages, somatic cells, natural killer cells release immunoreactive substances induce interferon, interleukin other aspects of the performance of a variety of physiological activity. The principle of one of its anti-virus is to improve the ability of patients with leukocyte interferon inducible, normal people taking astragalus the grass extract tablets IgE3 significant increase. Astragalus can promote macrophage phagocytic function, can promote the proliferation of B cells and inhibition of total complement activity. Produce interleukin-induced promotion of mouse lymphocytes immunospecific rosette formation of sheep blood cells, immune dysfunction caused by the immunosuppressant significant protective effect, with a two-way role immunomodulatory agent. APS is Astragalus immune activity substances, it can enhance the phagocytic function, from the spleen and thymus weight, hemolysin, hemagglutinin and the total number of spleen cells and plaque forming cell assay seen, APS, of HPS can complete and partial antagonism of the immunosuppressive effects of cyclophosphamide or prednisolone.

The role of cell-mediated immunity Astragalus may promote immune function of the body cells.

Enhance human blood lymphocytes immune function may be due in part to reduce the results of suppressor T cell activity. Astragalus polysaccharide activated T lymphocytes within of IL-2mRNA and IL-2RmRNA, gene transcription by regulating the content as well as to promote the metabolism of phosphatidylinositol, thus improving post-traumatic expression, this may be the mechanism of cellular immune function Astragalus polysaccharide corrective post-traumatic a. Astragalus may be related to the regulatory role of T cells and their secretion of cytokines regulating the generation of IgG subclasses.

The impact of natural killer cells

The Astragalus may protect target cells against T cell activity, but its extent as the role of T cell activity. It improves the effect of NK cell activity by inducing lymphocytes produce interferon type II mediators. Therefore considered that NK cells may be T-cell precursor cells, Astragalus on NK cells with it the role of T cell activation is consistent.

Induce interferon

Astragalus significant stimulation of the interferon system, including self-induced, promote inducible and active play three. Astragalus itself a certain degree of Helps Strengthen Immune Response effect, astragalus polysaccharide (5mg/kg) IL-2/LAK Helps Strengthen Immune Response effect, enhanced IL-2/LAK Helps Strengthen Immune Response effect.

Impact on metabolism

2.1 cell metabolism through the observation of human fetal kidney cells, fetal lung diploid cells and mouse kidney cells grown in nutrient solution containing Astragalus Astragalus found physiological metabolism of the cells can be enhanced. The mice decoction and normal controls after to take astragalus dry extract tablets the plasma CAMp content has improved significantly. Mice SC injection, a significant increase in the total number of white blood cells and the number of polymorphonuclear leukocytes. Astragalus also to promote the generation of the various types of blood cells, the development and maturation of the process, promote hematopoietic function of the bone marrow. On cultured liver cells, astragalus can promote RNA and protein synthesis, suggesting that it can extend the life span of cells, enhance cell metabolism postponed aging.

2.2 of nucleic acid metabolism

Astragalus polysaccharide (ASP), the degree of inhibition of the vitality of the free RN-ase: kidney <liver <lung <spleen, the results of application of the relative rate of increase of the equilibrium reaction to explain the role of APS in the low RI organizational performance significantly. Astragalus inhibit human lung diploid cell RNA metabolism, Astragalus decoction can significantly promote bone marrow cell DNA synthesis, speed up the nuclear process of cell division. The astrageloside regenerating liver DNA content can significantly increase, no significant effect of astragalus polysaccharides on DNA metabolism.

2.3 inner loop nucleotides

Astragalus decoction can significantly increase the plasma and tissue of mice the inner loop nucleotide (cAMP and Cgmp), the content of its organ is different; administration increases of cAMP, cGMP decreased; liver contrast ; spleen increased. Further experiments showed that Astragalus on cAMP effects are caused due to their inhibition of cyclic adenosine monophosphate - phosphodiesterase (cAMP-PDE).

2.4 pairs of proteins and other metabolic

Mice with Astragalus decoction intragastrically for 10 days, can significantly increase H-leucine incorporation of the rate of protein of the serum, liver, while no effect on the protein content, i.e. Astragalus may promote mouse serum and protein profile, and wherein the polysaccharide is likely to promote the protein profile of the active ingredient. Astrageloside 100g/kg gavage also have a similar effect. Astragalus animal insulin hypoglycemia, elevated blood sugar levels, but the margin of increase is smaller. Role on the cardiovascular system

Of 3.1 on the heart

Astragalus decoction on isolated frog heart, alcohol extract enables enhanced cardiac contractility isolated frog or toad, the amplitude significantly expanded, high-dose inhibition. So astrageloside may be achieved through the NA, K-ATP enzyme cardiac function. According to reports, Astragalus make human cardiomyocytes lactate dehydrogenase and succinate dehydrogenase content increased. The above prompted astragalus with calcium antagonism can reduce traffic viral infection caused by myocardial CA, it is possible to mitigate the secondary CA damage of the infected cells, and inhibit the replication of viral RNA in the cells, showing its viral myocarditis on the clinical application value. But single dose Astragalus CVB3 myocarditis prevention. The astrageloside positive inotropic effect on myocardial similar products with cardiac glycosides. Experiments show that: Radix can significantly improve the myocardial infarction canine cardiac contractility, enhanced coronary flow, has a protective effect on the heart function. Astragalus role of oxygen free radicals may be one of the mechanisms of cardiac function. Astragaloside IV injection effective non-digitalis inotropic products.

3.2 blood vessels, blood pressure

Astragalus expansion of the role of blood vessels and expansion of coronary. It is felt that the antihypertensive effect is a direct result of peripheral expansion, no dependencies with heart, and histamine release or adrenergic receptors. Astragalus on blood pressure and renin - angiotensin - aldosterone system, carnosine with central nervous peptides, release the enzyme - Carnosine system, and hydroxyproline were. Astragalus buck ingredients had that the bound alkaline substances, but later found that Astragalus plant root contains amino butyric acid content correlated with the antihypertensive effect of the strength of almost completely parallel, it is felt that buck the active ingredient. Vascular effects aminobutyric acid and can not be completely representative of the astragalus. Varying degrees of Astragalus can promote vascular endothelial cell migration and proliferation, and is conducive to promoting the process of angiogenesis. The Astragalus membranaceus of Astragalus saponin Ⅱ Ⅲ Ⅳ saponins and the formononetin, calycosin Isoflavonoids hatch red blood cell deformability significant improvement, this is to the Astragalus membranaceus improve hemorheology important mechanism, Astragalus is an important part of the role of human erythrocyte membranes may be the protection of human erythrocyte membranes from free radical attack.

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Astragalus Root Herbs Extract Powder "Immune System" Astrag Polysaccharide >80%
Astragalus Root Herbs Extract Powder "Immune System" Astrag Polysaccharide >80%
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